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! Ingredients !! Result
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| Sigil of Madawc + Sigil of Talic + Sigil of Korlic || Relic of the Ancients
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| Any 3 uber organs (Mephisto's Brain, Diablo's Horn, Baal's Eye) + Key || Pandemonium Talisman
| Prime Evil Soul + Black Soulstone + Pure Demonic Essence || Vision of Terror
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| Prime Evil Soul + Trang-Oul's Jawbone + Splinter of the Void + [[Hellfire Torch]] || Voidstone
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| 2 Ancient Bone Fragments + [[Hellfire Torch]] || Trang-Oul's Jawbone
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Relic of the Ancients, Pandemonium Talisman, Vision of Terror, and Voidstone are new items in PD2, asand areall thetheir ingredients for Vision of Terror and most of(except the ingredientsuber for Voidstone. Characters can no longer freely exit/re-enter Uber Tristram while enemies remain within,organs and theHellfire sameTorch) applies to theare new Diablo-Clone fight. Uber Organs now have a 45% droprate instead of 100%items.
* '''Pandemonium Talisman''' grants access to [[Monsters#Ubers|Uber Tristram]] for all players near the blood fountain (replaces the direct portal that used to be made with 1 of each uber organ)
** '''Mephisto's Brain''' drops from Uber Izual in the Furnace of Pain
** '''Diablo's Horn''' drops from Lilith (sometimes referred to as Uber Andariel) in the Matron's Den
** '''Baal's Eye''' drops from Uber Duriel in the Forgotten Sands
* '''Vision of Terror''' grants access to the new [[Monsters#Diablo-Clone|Diablo-Clone]] fight for all players near the blood fountain (DClone no longer randomly appears when [[Rings#The_Stone_of_Jordan|Stones of Jordan]] are sold to merchants)
** '''Prime Evil Soul''' drops from Diablo/Baal in Hell difficulty (1% chance - unconfirmed)
** '''Black Soulstone''' drops from [[Monsters#Ubers|Uber Tristram]] bosses (10% chance)
** '''Pure Demonic Essence''' drops from [[Maps|Map]] bosses (1% chance - unconfirmed)
* '''Voidstone''' grants access to [[Monsters#Rathma|Rathma]]
** '''Prime Evil Soul''' drops from Diablo/Baal in Hell difficulty (1% chance - unconfirmed)
** '''Splinter of the Void''' drops from [[Maps|Shadow of Mendeln]] map event (5% chance)
** '''Trang-Oul's Jawbone''' drops from undead enemies (1:300k chance in Hell, less in other difficulties); can also be crafted using '''Ancient Bone Fragments''' which drops from those same enemies (1:100k chance in Hell, less in other difficulties)
** [[Hellfire Torch]]
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